Another name for Cushing’s disease is pituitary-dependent Cushing’s syndrome. Cushing’s disease specifically refers to cases of Cushing’s syndrome caused by a pituitary adenoma, which is a benign tumor in the pituitary gland. The adenoma produces excessive amounts of adrenocorticotropic hormone (ACTH), which in turn stimulates the adrenal glands to overproduce cortisol. The term “Cushing’s disease” is used to distinguish this specific cause of Cushing’s syndrome from other causes, such as adrenal tumors or exogenous corticosteroid use.
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