Which drugs cause angioedema?

Several drugs have been associated with the development of angioedema as a potential side effect. Some of the medications known to have the potential to cause angioedema include:

  1. Angiotensin-Converting Enzyme (ACE) Inhibitors: These medications are commonly used to treat high blood pressure (hypertension) and certain heart conditions. Examples include lisinopril, enalapril, ramipril, and captopril. ACE inhibitors have been known to cause angioedema, particularly in individuals with a predisposition to this side effect.
  2. Non-Steroidal Anti-Inflammatory Drugs (NSAIDs): Although relatively rare, certain NSAIDs, such as ibuprofen, aspirin, and naproxen, have been associated with angioedema in some individuals.
  3. Angiotensin Receptor Blockers (ARBs): ARBs, including medications like losartan, valsartan, and irbesartan, are commonly used to treat hypertension and certain heart conditions. While angioedema is less common with ARBs compared to ACE inhibitors, it can still occur as a potential side effect.
  4. Certain Antibiotics: Some antibiotics have been reported to cause angioedema in susceptible individuals. Examples include penicillin and cephalosporins. It is important to note that not everyone who is allergic to penicillin will develop angioedema, and not all cases of angioedema are caused by antibiotics.
  5. Other Medications: Certain medications used for the treatment of migraines (e.g., triptans), diuretics (e.g., furosemide), anticonvulsants (e.g., phenytoin), and immunomodulatory drugs (e.g., interferons) have also been linked to angioedema in some cases.

It is important to remember that angioedema as a side effect of these medications is relatively rare, and most individuals taking these drugs do not experience angioedema. However, if you have a known sensitivity or history of angioedema, it is crucial to inform your healthcare provider so that they can consider alternative medications or closely monitor your condition.

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If you experience symptoms of angioedema or suspect a medication is causing it, it is essential to seek medical attention for proper evaluation, diagnosis, and management.