Which antihistamine is best for anaphylaxis?

During an anaphylactic reaction, the primary and most important treatment is epinephrine (adrenaline). Epinephrine is administered as the first-line treatment through an auto-injector, such as an EpiPen. It rapidly counteracts the allergic response, constricts blood vessels, relaxes airway muscles, and helps maintain blood pressure. Antihistamines, while they can help relieve certain symptoms associated with anaphylaxis, … Read more